Low-Energy Diet Induces Different Effects in Men, Women

Men had larger reductions in metabolic syndrome Z-score, C-peptide, fat mass, heart rate.

PSA Level 3 Months After Radiation Treatment May Predict Outcome

Findings for men with intermediate- and high-risk prostate cancer

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

Men with higher estradiol and estradiol/testosterone levels had an increased risk for pulmonary arterial hypertension.

Screening for Prostate Cancer: USPSTF Recommendation Statement

The USPSTF has updated its 2012 recommendations on prostate-specific antigen (PSA)-based screening for prostate cancer.

Prostate-specific antigen screening helps prostate cancer detection

Prostate cancer was diagnosed more frequently in men who underwent single prostate-specific antigen screening than in those who did not, but mortality was unaffected.

Aggressive treatment not beneficial for metastatic prostate cancer

For men with metastatic prostate cancer, aggressive therapy has no significant advantage over conservative androgen deprivation only treatments.

Prostate cancer recurrence linked to metabolic syndrome, obesity

A positive correlation between increased BMI and risk of prostate cancer recurrence was observed in patients undergoing radical prostatectomy.

Clinical tool may help in prostate cancer screenings

Polygenic hazard scores were developed to help predict the age of onset of prostate cancer.

Ibuprofen use may compromise reproductive health in men

Increased ibuprofen administration elevates LH and decreases testosterone to LH and inhibin B to FSH ratios in young adult men.

Sperm counts significantly declining in men from North America, Europe

Western males saw the most significant sperm count decline at 52.4%.

Surgery may not improve outcomes in early-stage prostate cancer

A 20-year study found that patients with early-stage prostate cancer who have surgery to remove their tumor do not live longer than those who receive no treatment.

USPSTF recommends individualized approach to prostate cancer screening

The USPSTF recommends that prostate cancer screenings should be an individual decision.

Antiandrogen therapy improves long-term survival after prostate cancer returns

Antiandrogen therapy with daily bicalutamide to salvage radiation therapy resulted in significantly higher rates of long-term overall survival.

High red meat consumption linked to diverticulitis in men

Unprocessed red meat was associated with an increased risk of diverticulitis.

American Urological Association issues guideline for male urethral stricture

The guidelines provide a clinical framework for the diagnosis and treatment of male urethral stricture.

Testosterone treatment may increase risk of venous thromboembolism

Researchers sought to determine the risk of venous thromboembolism associated with use of testosterone treatment.

Is vasectomy linked to risk of prostate cancer?

Vasectomy can continue to be a safe method of contraception in men.

More than half of US citizens have a chronic health condition

Conditions such as chronic disease, mental illness, or substance abuse commonly overlap with each other and with poverty, which contributes to poor health.

STD cases reach record high in the U.S.

The largest increase in reported STD cases occurred in P&S syphilis, gonorrhea and chlamydia.

Liver hepatotoxicity results from herbal, dietary supplements

The ultimate goal should be to more closely regulate potentially injurious ingredients in herbal and dietary supplements.

Androgen-deprivation therapy may increase risk of dementia

Patients with prostate cancer receiving androgen-deprivation therapy may have a greater risk of dementia.

USPSTF releases statement on genital herpes screening

A Grade D recommendation discourages routine screening in asymptomatic adolescents and adults.

Testosterone treatment beneficial in older men

Men 65 years of age and older who received 1 year of testosterone therapy reported better mood and fewer depressive symptoms.

Parental caffeine consumption linked to elevated risk of early miscarriage

Drinking 2 or more caffeinated beverages per day has been linked to elevated risk of miscarriage early in pregnancy.

Asthma prevalence higher in obese adults

A National Center for Health Statistics study found significantly higher rates of asthma prevalence among obese women compared with men.

Sexual identity disclosure linked to elevated rates of HIV testing, hepatitis vaccinations

Men who have sex with men who disclosed their sexual identity to their providers were more likely to receive appropriate health services, including routine HIV testing and hepatitis vaccinations.

MI risks, symptoms different in women compared with men, per AHA

Women and men experience different symptoms, risks, and outcomes of myocardial infarction.

Initiating alpha-blocker therapy linked to higher risk of stroke in men

Investigators found an increased risk of ischemic stroke among all patients within 21 days following initiation of alpha-blocker therapy.

Diagnostic factors help patients avoid confirmatory prostate biopsy

The analysis of diagnostic characteristics may predict the result of a confirmatory biopsy.

Prostate cancer treatment linked to Alzheimer's risk

Patients treated with androgen deprivation therapy had a 1.88-times increased rate of developing Alzheimer's disease.

Active surveillance of low-risk prostate cancer patients may not be efficient

New research suggests that men with low-risk prostate cancer who undergo choose watchful waiting may not receive timely treatment when compared to those undergoing active treatment.

Reduction in number of men screened for and diagnosed with prostate cancer

In the United States, the rate of prostate cancer screening is down, and the number of men diagnosed with the disease has also dropped.

Active surveillance 
encouraged for prostate cancer screening

Men should regularly be screened for prostate cancer, the leading cause of cancer death for men in the United States.

Very high, very low physical activity increases heart failure risk

Extremely high and low amounts of physical activity increase heart failure risk in men.

More radiation does not increase survival in low-risk prostate cancer

Higher doses of radiation does not increase survival rates in low-risk prostate cancer.

Lifestyle, not ED medication, raises melanoma risk

Men who took erectile dysfunction medication had increased risk for melanoma, but it is probably due to lifestyle factors.

Targeted PSA screening prevents overdiagnosis, overtreatment

More targeted efforts needed for prostate-specific antigen screening.

Possible link between male sex hormones, psoriasis severity

Male patients with psoriasis have higher levels of estradiol and lower levels of testosterone compared with controls.

Paternal age linked to increased cancer risk

There was no association between having an older mother and increased risk of these cancers.

New adult congenital heart disease guidelines released

Adult patients diagnosed with congenital heart failure need to seek routine follow-up care.

Radiation, hormone therapy for prostate cancer

Combination radiation and hormone therapy is more effective than hormone therapy alone for the treatment of prostate cancer.

Selenium, vitamin E supplements do not reduce cataract risk in men

Long-term selenium and vitamin E supplementation did not reduce apparently healthy male patients' risks of developing age-related cataracts.

Weight loss strategies yield similar results in men, women

Although men lost more weight than women, the evidence does not indicate that weight loss strategies should differ according to sex.

FDA reconsidering ban on blood donations from men who have sex with men

The FDA is releasing draft guidance that would allow blood donations from men who have sex with men.

Obesity comorbid in half a million cancers

Excess weight was associated with 5.4% (n=345,000) of new cancers in women and 1.9% (n=136,000) of new cancers in men in 2012.

High trans fat consumption tied to worse memory in men

Men who ate more trans fat demonstrated notably worse performance on the word memory test.

HPV vaccine does not protect against recurrent warts in men

The only significant factor in the recurrence of genital warts was marital status.

DHEA serum levels predict coronary heart disease risk

For elderly men, low serum levels of the adrenal sex hormone DHEA and its sulfate, DHEA-S, predict coronary heart disease risk.

Mental stress affects heart differently in men, women

Compared with women, though, men were more likely to show changes in traditional physiological measures such as blood pressure.

Half of HIV-positive men who have sex with men aren't receiving antiretroviral therapy

Younger men and minority males were at highest-risk of not getting HIV-related treatment.

Five healthy habits may prevent 79% of heart attacks in men

Initial myocardial infarctions could be prevented in four out of five male patients with a proper combination of healthy lifestyle choices.

Primary-care providers can help identify intimate-partner violence

More than half of the male survey respondents who reported violence against their spouse or partner had at least one routine health visit within the past year.

Fitness delays age-related hypertension in males

Male patients who reported a high level of cardiorespiratory fitness postponed increases in age-related diastolic and systolic blood pressure levels.

Metabolic benefits of fenofibrate greater for women

Lipoprotein improvements from fenofibrate greater for women than men; CVD event reduction similar.

Chemicals found in plastics, household products reduce testosterone

Chemicals found in many household products may reduce androgen levels in both sexes.

Primary care after PCa

PCPs should encourage physical activity, smoking cessation, and a healthy diet for PCa survivors.

Screen men for abdominal aneurysm

The USPSTF document noted that the prevalence of AAA is 3.9% to 7.2% in men and 1.0% to 1.3% in women.

Testicular cancer risk up in Hispanic patients

A 58% increase in incidence rate per 100,000 has been noted from 1992 to 2010.

No link between testosterone therapy, heart attack

High-risk patients treated with testosterone had a lower rate of heart attacks compared with patients who did not receive treatment.

Be prepared to recognize STIs in women

About 20 million new STIs are diagnosed each year in the United States, with half occurring in young people aged 15 to 25 years.

Puberty causes differences in caffeine response between genders

Responses to caffeine vary across the menstrual cycle in postpubertal female patients.

Cohabiting males less likely to receive routine health checks

Only 50% of male patients living with unmarried partners underwent cholesterol and diabetes screenings.

Makers of erectile dysfuction drug Cialis seek OTC approval

The FDA would need additional research to sell the erectile dysfunction drug over-the-counter.

Can CVD patients get too much exercise?

Intensive exercise may not benefit patients with existing heart conditions.

New imaging methods better for prostate CA detection

Multiparametric magnetic resonance imaging reported high accuracy in diagnosing low-risk prostate cancers.

Prostate cancer care measures vary by region

Low adherence rates for prostate cancer care may be target for future quality improvements.

Prostatectomy cuts mortality in early prostate CA

Risk of long-term mortality is lower compared with watchful waiting.

FDA to review testosterone therapy risk

Investigation prompted by two recent studies citing possible elevated cardiovascular risks with testosterone therapy.

Former inmate wins malpractice lawsuit against State of Hawaii

A mistreated scrotal infection eventually led to castration.

Melatonin linked to lower prostate CA risk

Risk for advanced prostate cancer was 75% lower in men with high levels of 6-sulfatoxymelatonin -- a measure of melatonin breakdown in urine.

ADHD drugs linked to priapism

The FDA is warning of a rare but serious risk of painfully prolonged erections with ADHD drugs containing methylphenidate.

Baseline inflammation lowers prostate cancer risk on repeat biopsy

Even after adjustment, acute, chronic inflammation linked to lower PCa risk at two-year repeat biopsy.

Nonsurgical option available for Peyronie's disease

The FDA has approved Xioflex to treat the connective tissue disorder.

Prostate biopsy causes anxiety even when negative

Potential psychological harm associated with biopsy even in absence of cancer diagnosis

Resveratrol blocks exercise benefits in men

Older men who take resveratrol supplements may be depriving themselves of the cardiovascular benefits they should be getting from exercise.

Coffee protective against prostate CA recurrence

Drinking coffee may lower the risk for prostate cancer recurrence and disease progression.

Men don't rely on prostate-screen decision aids

Aids help men make more informed choices regarding PSA screening, but did not affect actual screening rates.

Restless legs syndrome linked to higher mortality in men

Study shows a significant correlation between men with restless legs syndrome and mortality.

Obesity increases colorectal cancer risk in men

Colorectal cancer prevention efforts should encourage the achievement and maintenance of a healthy body weight in addition to regular screenings

Consuming more vegetable fat may cut prostate cancer mortality

Replacing carbohydrates and animal fat with vegetable fat may reduce prostate cancer mortality.

Boyhood ADHD tied to adult obesity

Higher rates of obesity and higher BMIs observed in men with remitted ADHD versus men with no ADHD history.

FDA approves Xofigo for advanced prostate cancer

Xofigo has been approved three months ahead of schedule to treat men with metastatic castration-resistant prostate cancer.

Biases identified in primary care prostate-cancer screening

Primary-care practitioner beliefs about prostate-cancer screening account for much of the variability in the use of an informed-decision-making process.

Exercise cuts prostate cancer risk in whites

Regular, moderate exercise was associated with decreased prostate cancer risk in white, but not black, men.

FDA approves Zytiga for advanced prostate cancer

The FDA has expanded the indication for abiraterone acetate to include treating late-stage castration-resistant prostate cancer before the administration of chemotherapy.

AAP: Earlier puberty onset noted in U.S. boys

American boys are 6 months to 2 years younger at puberty onset today compared with studies dating back to the 1930s.

Tomatoes may lower stroke risk in men

Lycopene, an antioxidant found in high concentrations in tomatoes and tomato products, may lower stroke risk in men.

FDA approves prostate cancer imaging agent

Choline C 11 Injection, a PET scan imaging agent, is now available for men with elevated PSA levels after earlier treatment for prostate cancer.

Eating chocolate may lower stroke risk for men

Moderate chocolate consumption lowered the risk for any type of stroke 17% to 19%.

Decline in circumcisions may increase infections and costs

Estimates project that decreases in male circumcision rates would likely correlate with greater prevalence of sexually transmitted diseases and medical costs in both men and women.

CDC revises guidelines for gonorrhea treatment

Updated guidelines no longer recommended cephalosporins as first-line therapy.

Zaltrap approved for advanced colorectal cancer

The FDA has approved ziv-aflibercept (Zaltrap, Sanofi-Aventis) in combination with a FOLFIRI regimen for adults with advanced metastatic colorectal cancer.

FDA approves new test for prostate cancer

The Prostate Health Index is a non-invasive blood test that is 2.5-times more specific in detecting prostate cancer than prostate-specific antigen in patients with PSA values in the 4-10 ng/mL range.

USPSTF recommends against PSA-based screening

Based on the evidence, the U.S. Preventive Services Task Force gave a grade D recommendation against PSA-based screening for men in the general U.S. population, regardless of age.

Uncertainty common when deciding to stop PSA screening

Many clinicians find it difficult to determine when it's appropriate to stop screening patients for prostate cancer.

Chronic pain meds lower testosterone levels

Men taking daily long-acting opioids were nearly five times more likely to become hypogonadal than were men on short-acting opioids.

Jury still out on value of PSA screening

Extended follow-up data from the European Randomized Study of Screening for Prostate Cancer shows screening reduced risk of death from prostate cancer, but not all-cause mortality.

ACP issues colorectal cancer screening guidance

The American College of Physicians recommends clinicians begin screening average-risk individuals for colorectal cancer at age 50 years.

Male-pattern baldness linked to prostate symptoms

Early-onset androgenetic alopecia, or male-pattern baldness, may be a marker of urinary symptoms associated with an enlarged prostate, data indicate.

Insomnia increases cardiovascular risk, testosterone protective

Although low serum testosterone is associated with increased adiposity, an adverse metabolic risk profile, and atherosclerosis, few studies have shown a protective link between endogenous testosterone and cardiovascular events, until recently.

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