Pain Management Information Center
Odds of Death Up With Exposure to Pregabalin, Opioids
Dose-response association with highest odds of opioid-related death with high-dose pregabalin.
Low Literacy Self-Management Program for Chronic Pain May Be Effective
A low-literacy, pain self-management program delivered one-on-one by a health educator or in groups with lectures from experts over a period of 6 months may improve chronic pain outcomes.
Chronic Low Back Pain Levels Vary Between Sex and Race
Differences exist in race and gender in patients with chronic lower back pain, especially in pain sensitivity and severity due to aftersensations from mechanical punctuate pain and deep muscle hyperalgesia.
Fewer Cervical Spine Injuries Seen With Motorcycle Helmet Use
Findings based on analysis of motorcycle accident victims by helmet use.
Combination Therapies for Low Back Pain, Sciatica May Not Have Added Benefit
There is a lack of evidence supporting the benefits of combination drug therapy over monotherapy for the management of low back pain and sciatica.
Wide Variations in Opioid Prescribing Practices for Surgical Procedures
Variation exists in opioid prescribing practices among clinicians in single-hospital systems, which prompts concern about the potential for opioid overprescribing.
Outpatient Opioid Prescriptions for Children Often Filled
Cumulative incidence of opioid-related adverse events was 38.3 per 100,000 prescriptions.
FDA to Review Novel Opioid Analgesic for Chronic Low Back Pain
This novel agent has low permeability across the blood-brain barrier, which slows its rate of entry into the brain and reduces dopamine release.
Postpartum Pain Management Recommendations From the American College of Obstetricians and Gynecologists
A committee from the American College of Obstetricians and Gynecologists formulated several recommendations for safely managing pain and fatigue in women during the early postpartum period.
Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients
Odds of pre-op opioid use up with age 31 to 40 years, tobacco use, illicit drug use, depression.
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